Journal article

Occupational exposure to pesticides are associated with fixed airflow obstruction in middle-age

SM Alif, SC Dharmage, G Benke, M Dennekamp, JA Burgess, JL Perret, CJ Lodge, S Morrison, DP Johns, GG Giles, LC Gurrin, PS Thomas, JL Hopper, R Wood-Baker, BR Thompson, IH Feather, R Vermeulen, H Kromhout, EH Walters, MJ Abramson Show all

Thorax | BMJ PUBLISHING GROUP | Published : 2017

Abstract

Rationale Population-based studies have found evidence of a relationship between occupational exposures and Chronic Obstructive Pulmonary Disease (COPD), but these studies are limited by the use of prebronchodilator spirometry. Establishing this link using postbronchodilator is critical, because occupational exposures are a modifiable risk factor for COPD. Objectives To investigate the associations between occupational exposures and fixed airflow obstruction using postbronchodilator spirometry. Methods One thousand three hundred and thirty-five participants were included from 2002 to 2008 follow-up of the Tasmanian Longitudinal Health Study (TAHS). Spirometry was performed and lifetime work ..

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