How does performance of the Friedreich Ataxia Functional Composite compare to rating scales?
Geneieve Tai, Eppie M Yiu, Martin B Delatycki, Louise A Corben
JOURNAL OF NEUROLOGY | SPRINGER HEIDELBERG | Published : 2017
Progression of Friedreich ataxia (FRDA) is often measured using neurological rating scales such as the Friedreich Ataxia Rating Scale (FARS). Performance scales comprising functional measures have been used in other conditions due to their increased sensitivity and reproducibility and may replace examination-based measures. The aims of this study were to examine the relationship between the Friedreich Ataxia Functional Composite (FAFC) measures and characteristics of FRDA to determine if the FAFC is more sensitive to clinical change over time compared to its components. One hundred and twenty-two individuals completed the timed 25-foot walk (T25FW), 9-Hole Peg Test (9HPT) and the low-contras..View full abstract
This study was supported by the Victorian Government's Operational Infrastructure Support Program. GT reports no disclosures. EMY is supported by a National Health Medical Research Council (NHMRC) Early Career Fellowship. MBD receives grant support from NHMRC. LAC reports no disclosures.