Journal article

Standardized measurement of sensorimotor recovery in stroke trials: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable

Gert Kwakkel, Natasha A Lannin, Karen Borschmann, Coralie English, Myzoon Ali, Leonid Churilov, Gustavo Saposnik, Carolee Winstein, Erwin EH van Wegen, Steven L Wolf, John W Krakauer, Julie Bernhardt

INTERNATIONAL JOURNAL OF STROKE | SAGE PUBLICATIONS LTD | Published : 2017

Abstract

Finding, testing and demonstrating efficacy of new treatments for stroke recovery is a multifaceted challenge. We believe that to advance the field, neurorehabilitation trials need a conceptually rigorous starting framework. An essential first step is to agree on definitions of sensorimotor recovery and on measures consistent with these definitions. Such standardization would allow pooling of participant data across studies and institutions aiding meta-analyses of completed trials, more detailed exploration of recovery profiles of our patients and the generation of new hypotheses. Here, we present the results of a consensus meeting about measurement standards and patient characteristics that..

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Grants

Awarded by NHMRC


Awarded by NHMRC TRIP fellowship


Awarded by Chief Scientist Office


Funding Acknowledgements

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: JB was supported by NHMRC (1058635) and NL holds a NHMRC TRIP fellowship (GNT1112158).We acknowledge the following organizations for their financial support of the meeting: NHMRC CRE Stroke Rehabilitation & Brain Recovery (Australia), Heart and Stroke Foundation of Canada, Heart and Stroke Foundation Canadian Partnership for Stroke Recovery. An unrestricted educational grant was provided by Ipsen Pharma. The Florey Institute of Neuroscience and Mental Health acknowledges support from the Victorian Government, in particular funding from the Operational Infrastructure Support Grant.