Journal article

Macrolide resistance in pneumococci-is it relevant?

Allen C Cheng, Adam WJ Jenney

PNEUMONIA | GRIFFITH UNIV EPRESS | Published : 2016

Abstract

Macrolide antibiotics are widely used for a range of indications, including pneumonia. Both high-level and low-level resistance to macrolides is increasing in pneumococci globally. Macrolide resistance in pneumococci is of limited clinical relevance where ß-lactams remain the mainstay of treatment, such as for moderate/severe pneumonia; however, data suggest that macrolides may not be able to be relied on as monotherapy for serious pneumococcal infections.

University of Melbourne Researchers