Macrolide resistance in pneumococci-is it relevant?
Allen C Cheng, Adam WJ Jenney
PNEUMONIA | GRIFFITH UNIV EPRESS | Published : 2016
Macrolide antibiotics are widely used for a range of indications, including pneumonia. Both high-level and low-level resistance to macrolides is increasing in pneumococci globally. Macrolide resistance in pneumococci is of limited clinical relevance where ß-lactams remain the mainstay of treatment, such as for moderate/severe pneumonia; however, data suggest that macrolides may not be able to be relied on as monotherapy for serious pneumococcal infections.
AC is supported by a NHMRC Career Development Fellowship.