Journal article

Quantifying child mortality reductions related to measles vaccination

JD Goldhaber-Fiebert, M Lipsitch, A Mahal, AM Zaslavsky, JA Salomon

Plos One | PUBLIC LIBRARY SCIENCE | Published : 2010

Open access

Abstract

Background: This study characterizes the historical relationship between coverage of measles containing vaccines (MCV) and mortality in children under 5 years, with a view toward ongoing global efforts to reduce child mortality. Methodology/Principal Findings: Using country-level, longitudinal panel data, from 44 countries over the period 1960-2005, we analyzed the relationship between MCV coverage and measles mortality with (1) logistic regressions for no measles deaths in a country-year, and (2) linear regressions for the logarithm of the measles death rate. All regressions allowed a flexible, non-linear relationship between coverage and mortality. Covariates included birth rate, death rat..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

The research was supported in part by a training grant in the Epidemiology of Infectious Diseases and Biodefense from the United States' National Institutes of Health's (NIH) National Institute of Allergy and Infectious Disease administered via the Harvard School of Public Health made to Dr. Goldhaber-Fiebert during the final year of his doctoral dissertation. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.