Journal article
Assessment of oxidative stress biomarkers in exhaled breath condensate and blood of thoroughbred foals
E Po, C Williams, G Muscatello, P Celi
Veterinary Journal | ELSEVIER SCI LTD | Published : 2013
Abstract
This study reports preliminary data on systemic and local biomarkers of oxidative stress (OS) in Thoroughbred foals. Blood and exhaled breath condensate (EBC) were sampled from 13 foals on two farms. Values of reactive oxygen metabolites (d-ROMs), biological antioxidant potential (BAP), antioxidant barrier (OXY-ads), thiol antioxidant barrier (SHp) and advanced oxidation protein products (AOPPs) were determined in blood, while EBC samples were assayed for hydrogen peroxide (H2O2) levels.Systemic and local OS biomarkers did not differ between farms and gender. Increased oxidative stress index (OSI) values in a foal recovering from pneumonia and elevated H2O2 in EBC coupled with low SHp and el..
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Funding Acknowledgements
The authors wish to acknowledge the Honda Foundation for providing financial support to purchase the Free Radical Elective Evaluator (FREE) System. The authors are grateful for the full cooperation of the two Thoroughbred studs involved in this study. This research was funded by the Rural Industries Research and Development Corporation (RIRDC).