Journal article

Relationship between late embryonic mortality and the increase in plasma advanced oxidised protein products (AOPP) in dairy cows

Pietro Celi, Mariacristina Merlo, Laura Da Dalt, Annalisa Stefani, Olimpia Barbato, Gianfranco Gabai



The involvement of protein oxidation in embryonic mortality (EM) has been poorly investigated in cows. Advanced oxidation protein products (AOPP) are markers of protein oxidation generated by activated neutrophils and involved in inflammation. The aim of this work was to study AOPP in cow plasma and their relationship with late EM. The outcomes of 158 artificial inseminations (AI) were examined in 72 cows, which were classified ex post on the basis of blood progesterone and pregnancy-associated glycoprotein concentrations and clinical confirmation of pregnancy into the following categories: (1) positive (AI+, resulted in pregnancy, n=58), (2) negative (AI-, did not result in pregnancy, n=86)..

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University of Melbourne Researchers


Awarded by Italian Ministry of University and Research (MIUR)

Funding Acknowledgements

This study was supported by the Italian Ministry of University and Research (MIUR, PRIN 2005, grant number 2005075783_003). The authors are grateful to Mr Giancarlo Lanfredi and Mr Sauro Malagoli, owner and director of the commercial farm Fienilnuovo, and to Mr Giuseppe Gorlani, owner of the commercial farm Go-All. Particular thanks to Mr Tommaso Brogin for his skilled technical support. There is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.