Journal article

Innovative technology shows impact of glycaemic control on peripheral retinal vessels in adolescents with type 1 diabetes

Valli Velayutham, Paul Z Benitez-Aguirre, Maria E Craig, Gerald Liew, Tien Y Wong, Alicia J Jenkins, Kim C Donaghue

DIABETOLOGIA | SPRINGER | Published : 2017

Abstract

AIMS/HYPOTHESIS: Retinal imaging enables non-invasive microvasculature assessment; however, only central retinal vessels have been studied in type 1 diabetes. Peripheral smaller vessels have a major haemodynamic role and may differ from central vessels in their response to the diabetic milieu. We hypothesise that diabetes has a greater impact on peripheral retinal vessels vs central vessels. METHODS: Retinal photographs from adolescents (n = 736; age 12-20 years) with type 1 diabetes were graded (Singapore I Vessel Assessment) with vessel calibres measured in the 'central zone' as central retinal arteriolar and venular equivalents (CRAE and CRVE, respectively) and the 'extended zone' as mean..

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