Journal article

Screening of the 'Open Scaffolds' collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the barber's pole worm and other parasitic nematodes

Sarah Preston, Yaqing Jiao, Jonathan B Baell, Jennifer Keiser, Simon Crawford, Anson V Koehler, Tao Wang, Moana M Simpson, Ray M Kaplan, Karla J Cowley, Kaylene J Simpson, Andreas Hofmann, Abdul Jabbar, Robin B Gasser

International Journal for Parasitology: Drugs and Drug Resistance | ELSEVIER SCI LTD | Published : 2017

Grants

Awarded by Victoria Life Sciences Computation Initiative, Australia (VLSCI) on its Peak Computing Facility at The University of Melbourne, Australia, an initiative of the Victorian Government, Australia


Funding Acknowledgements

The present study was funded by the National Health and Medical Research Council of Australia (NHMRC), the Australian Research Council (ARC) and the Wellcome Trust (RBG), and supported by a Victoria Life Sciences Computation Initiative, Australia (VLSCI; grant no. VR0007) on its Peak Computing Facility at The University of Melbourne, Australia, an initiative of the Victorian Government, Australia. Animal ethics approval (AEC no. 0707258) was granted by The University of Melbourne. We thank our colleagues at Medicines for Malaria Ventures (MMV) for their support. We expressly wish to acknowledge the efforts of the constructors of the 'Open Scaffold' library at Compounds Australia, David Camp, Graeme Stevenson, Mikhail Krasavin and Alain-Dominique Gorse. The Victorian Centre for Functional Genomics (KJS) is supported by funding from the Australian Government's Education Investment Fund through the Super Science Initiative and the Peter MacCallum Cancer Centre Foundation. We thank an anonymous reviewer for constructive comments and suggestions on our manuscript.