Journal article
Sustained versus standard inflations during neonatal resuscitation to preventmortality and improve respiratory outcomes
Matteo Bruschettini, Colm PF O'Donnell, Peter G Davis, Colin J Morley, Lorenzo Moja, Simona Zappettini, Maria Grazia Calevo
COCHRANE DATABASE OF SYSTEMATIC REVIEWS | WILEY | Published : 2017
Abstract
Background: At birth, infants' lungs are fluid-filled. For newborns to have a successful transition, this fluid must be replaced by air to enable effective breathing. Some infants are judged to have inadequate breathing at birth and are resuscitated with positive pressure ventilation (PPV). Giving prolonged (sustained) inflations at the start of PPV may help clear lung fluid and establish gas volume within the lungs. Objectives: To assess the efficacy of an initial sustained (> 1 second duration) lung inflation versus standard inflations (≤ 1 second) in newly born infants receiving resuscitation with intermittent PPV. Search methods: We used the standard search strategy of the Cochrane Neona..
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Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, USA
Funding Acknowledgements
Institute for Clinical Sciences, Lund University; Research & Development, Section for HTA Analysis, Skane University Hospital, Lund, Sweden.r Royal Women's Hospital, Melbourne, Australia.r University of Melbourne, Australia.r Istituto Giannina Gaslini, Genoa, Italy.r Murdoch Childrens Research Insitute, Australia.r National Health and Medical Research Council, Australia.r Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, USA.r Editorial support of the Cochrane Neonatal Review Group has been funded with Federal funds from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, USA, under Contract No. HHSN275201100016C