Comparing very low birth weight versus very low gestation cohort methods for outcome analysis of high risk preterm infants.
Louise Im Koller-Smith, Prakesh S Shah, Xiang Y Ye, Gunnar Sjörs, Yueping A Wang, Sharon SW Chow, Brian A Darlow, Shoo K Lee, Stellan Håkanson, Kei Lui, undefined Australian and New Zealand Neonatal Network, undefined Canadian Neonatal Network, undefined Swedish Neonatal Quality Register
BMC Pediatr | Published : 2017
BACKGROUND: Compared to very low gestational age (<32 weeks, VLGA) cohorts, very low birth weight (<1500 g; VLBW) cohorts are more prone to selection bias toward small-for-gestational age (SGA) infants, which may impact upon the validity of data for benchmarking purposes. METHOD: Data from all VLGA or VLBW infants admitted in the 3 Networks between 2008 and 2011 were used. Two-thirds of each network cohort was randomly selected to develop prediction models for mortality and composite adverse outcome (CAO: mortality or cerebral injuries, chronic lung disease, severe retinopathy or necrotizing enterocolitis) and the remaining for internal validation. Areas under the ROC curves (AUC) of the mod..View full abstract