Journal article
Early surgery and neurodevelopmental outcomes of children born extremely preterm
RW Hunt, LM Hickey, AC Burnett, PJ Anderson, JLY Cheong, LW Doyle
Archives of Disease in Childhood Fetal and Neonatal Edition | BMJ PUBLISHING GROUP | Published : 2018
Abstract
OBJECTIVES: To (1) compare the neurodevelopmental outcomes at 8 years of age of children born extremely preterm (EP) who underwent surgical procedures during the course of their initial hospital admission with those who did not and (2) compare the outcomes across eras, from 1991 to 2005.DESIGN: Prospective observational cohort studies conducted over three different eras (1991-1992, 1997 and 2005). Surviving EP children, who required surgical intervention during the primary hospitalisation, were assessed for general intelligence (IQ) and neurosensory status at 8 years of age. Major neurosensory disability comprised any of moderate/severe cerebral palsy, IQ less than -2 SD relative to term con..
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Awarded by National Health and Medical Research Council of Australia
Funding Acknowledgements
Supported by grants from the National Health and Medical Research Council of Australia (Centre of Clinical Research Excellence #546519; Centre of Research Excellence #1060733; Early Career Fellowship #1053787 to JC; Senior Research Fellowship #1081288 to PJA) and the Victorian Government's Operational Infrastructure Support Programme.