Journal article

Dysregulation of BCL-2 family proteins by leukemia fusion genes

Lauren M Brown, Diane T Hanna, Seong L Khaw, Paul G Ekert

Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2017

DOI: 10.1074/jbc.R117.799056

University of Melbourne Researchers

Seong Khaw Author Medical Biology (W.E.H.I.)

Paul Ekert Author Paediatrics Royal Children's Hospital

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Keywords

Proto-Oncogene Proteins C-Bcl-2

Biochemistry & Molecular Biology

Acute Lymphoblastic-Leukemia

Oncogene Proteins, Fusion

Oncogene Fusion

Life Sciences & Biomedicine

Cell Transformation, Neoplastic

Science & Technology

Tyrosine-Protein Kinase (tyrosine Kinase)

Gene Expression Regulation, Neoplastic

Models, Biological

Chronic Myeloid-Leukemia

Somatic Mutations

Expression Patterns

B-Cell Lymphoma 2 (bcl-2) Family

Translocation, Genetic

Precursor Cell Lymphoblastic Leukemia-Lymphoma

Cancer Development

Cell Proliferation