Fractional amplitude of low-frequency fluctuations (fALFF) in post-stroke depression
Natalia Egorova, Michele Veldsman, Toby Cumming, Amy Brodtmann
NEUROIMAGE-CLINICAL | ELSEVIER SCI LTD | Published : 2017
Depression is a common outcome following stroke, associated with reduced quality of life and poorer recovery. Despite attempts to associate depression symptoms with specific lesion sites, the neural basis of post-stroke depression remains poorly understood. Resting state fMRI has provided new insights into the neural underpinnings of post-stroke depression, but has been limited to connectivity analyses exploring interregional correlations in the time-course of activity. Other aspects of resting state BOLD signal remain unexamined. Measuring the amplitude of low frequency fluctuations allows the detection of spontaneous neural activity across the whole brain. It provides complementary informa..View full abstract
Awarded by National Health and Medical Research Council
This work was supported by the National Health and Medical Research Council project grant number APP1020526, the Brain Foundation, Wicking Trust, Collie Trust, and Sidney and Fiona Myer Family Foundation.