Book Chapter
Measuring Natural Selection
Anders Goncalves da Silva
BIOINFORMATICS, VOL I: DATA, SEQUENCE ANALYSIS, AND EVOLUTION, 2ND EDITION | Methods in Molecular Biology | SPRINGER | Published : 2017
Abstract
In this chapter, I review the basic algorithm underlying the CODEML model implemented in the software package PAML. This is intended as a companion to the software's manual, and a primer to the extensive literature available on CODEML. At the end of this chapter, I hope that you will be able to understand enough of how CODEML operates to plan your own analyses.