Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1

T-C Teh; N-Y Nguyen; DM Moujalled; D Segal; G Pomilio; S Rijal; A Jabbour; K Cummins; K Lackovic; P Blombery; E Thompson; PG Ekert; G Lessene; SP Glaser; DCS Huang; AW Roberts; MA Guthridge; AH Wei

Journal article

Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1

T-C Teh, N-Y Nguyen, DM Moujalled, D Segal, G Pomilio, S Rijal, A Jabbour, K Cummins, K Lackovic, P Blombery, E Thompson, PG Ekert, G Lessene, SP Glaser, DCS Huang, AW Roberts, MA Guthridge, AH Wei

Leukemia | NATURE PUBLISHING GROUP | Published : 2018

DOI: 10.1038/leu.2017.243

University of Melbourne Researchers

Guillaume Lessene Author Medical Biology (W.E.H.I.)

Ella Thompson Author The Sir Peter MacCallum Department of Oncology

David Huang Author Medical Biology (W.E.H.I.)

Paul Ekert Author Paediatrics Royal Children's Hospital

David Segal Author Medical Biology (W.E.H.I.)

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

We thank Leukemia Foundation, Victorian Cancer Agency, Arrow Bone Marrow Transplant Foundation, Leukemia Lymphoma Society, Australian Cancer Research Foundation, Victorian State Government Operational Infrastructure Support (OIS) and the National Health and Medical Research Council (fellowships and grants including an Independent Infrastructure Support Scheme grant 9000220); we also thank Abbvie for providing venetoclax and A-1155463.