5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats
Kulbhushan Tikoo, Idrish Yunus Ali, Jeena Gupta, Chanchal Gupta
Toxicology Letters | ELSEVIER IRELAND LTD | Published : 2009
We thank Mr. Anil Gaikwad and Mr. Praveen Bhuwal for providing their help in the initial stages of this work. This work was Supported by DPRP project grant from Department of Science and Technology and National Institute of Pharmaceutical Education and Research (NIPER). Cis-diamminplatinumdichloride (cisplatin, CP) was generously provided by Dabur India Pvt. Ltd.