Journal article

Echocardiographic Findings Predict In-Hospital and 1-Year Mortality in Left-Sided Native Valve Staphylococcus aureus Endocarditis Analysis From the International Collaboration on Endocarditis-Prospective Echo Cohort Study

Trine K Lauridsen, Lawrence Park, Steven YC Tong, Christine Selton-Suty, Gail Peterson, Enrico Cecchi, Luis Afonso, Gilbert Habib, Carlos Pare, Syahidah Tamin, Stuart Dickerman, Arnold S Bayer, Magnus C Johansson, Vivian H Chu, Zainab Samad, Niels E Bruun, Vance G Fowler, Anna Lisa Crowley

CIRCULATION-CARDIOVASCULAR IMAGING | LIPPINCOTT WILLIAMS & WILKINS | Published : 2015

Abstract

BACKGROUND: Staphylococcus aureus left-sided native valve infective endocarditis (LNVIE) has higher complication and mortality rates compared with endocarditis from other pathogens. Whether echocardiographic variables can predict prognosis in S aureus LNVIE is unknown. METHODS AND RESULTS: Consecutive patients with LNVIE, enrolled between January 2000 and September 2006, in the International Collaboration on Endocarditis were identified. Subjects without S aureus IE were matched to those with S aureus IE by the propensity of having S aureus. Survival differences were determined using log-rank significance tests. Independent echocardiographic predictors of mortality were identified using Cox-..

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University of Melbourne Researchers

Grants

Awarded by National Institutes of Health



Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES


Funding Acknowledgements

Dr Lauridsen was supported by a Fulbright scholarship and grants from the Danish Heart Foundation. Dr Bayer was supported by grant NIH-NIAID-RO1AI039108-16. Dr Fowler was supported by Grants K24-AI093969 and R01AI068804 from the National Institutes of Health. Dr Tong is an Australian National Health and Medical Research Council Career Development Fellow (1065736).