Poor utility of grading scales in acute intracerebral hemorrhage: results from the INTERACT2 trial
Emma Heeley, Craig S Anderson, Mark Woodward, Hisatomi Arima, Thompson Robinson, Christian Stapf, Mark Parsons, Pablo M Lavados, Yining Huang, Yanxia Wang, Sophie Crozier, Adrian Parry-Jones, Jiguang Wang, John Chalmers
INTERNATIONAL JOURNAL OF STROKE | WILEY-BLACKWELL | Published : 2015
BACKGROUND: Several simple clinical grading scores have been developed for intracerebral hemorrhage, primarily to predict 30-day mortality. AIMS: We aimed to determine the accuracy of three popular scores (original intracerebral hemorrhage, modified intracerebral hemorrhage, and intracerebral hemorrhage grading scale) on 30-day mortality and 90-day death or major disability, and whether the magnitude of benefit varies according to prognosis graded by the three predictive scores. METHODS: Data from the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial which included 2839 intracerebral hemorrhage patients (<6 hours) and elevated systolic blood pressure (150-220 mmHg), rando..View full abstract
The INTERACT2 study was supported by grants from the National Health and Medical Research Council (NHMRC) of Australia. Professor Anderson holds an NHMRC senior principal research fellowship.