Journal article

Perfusion computed tomography: Prediction of final infarct extent and stroke outcome

MW Parsons, EM Pepper, V Chan, S Siddique, S Rajaratnam, GA Bateman, CR Levi

ANNALS OF NEUROLOGY | WILEY-LISS | Published : 2005

Abstract

The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) has not been previously applied to perfusion CT (CTP). Five raters assigned ASPECTS to baseline noncontrast CT (NCCT), CT angiography source images (CTA-SI), CTP source images (CTP-SI), and CTP maps of cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time (MTT) from 37 consecutive patients with less than 6-hour anterior circulation ischemic stroke. Major reperfusion was identified on follow-up imaging. Mean baseline ASPECTS was compared with follow-up imaging ASPECTS. Rates of favorable outcome were compared for dichotomized baseline ASPECTS. In patients with major reperfusion, mean CBV and CTP-SI AS..

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