Journal article

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

Steve Eyre, John Bowes, Dorothee Diogo, Annette Lee, Anne Barton, Paul Martin, Alexandra Zhernakova, Eli Stahl, Sebastien Viatte, Kate McAllister, Christopher I Amos, Leonid Padyukov, Rene EM Toes, Tom WJ Huizinga, Cisca Wijmenga, Gosia Trynka, Lude Franke, Harm-Jan Westra, Lars Alfredsson, Xinli Hu Show all

Nature Genetics | NATURE PUBLISHING GROUP | Published : 2012

Grants

Awarded by Arthritis Research UK


Awarded by Swedish Research Council


Awarded by Redes Tematicas de Investigacion Cooperative en Salud (RETICS) Program, Instituto de Salud Carlos III, Spain


Awarded by Wellcome Trust


Awarded by US National Institutes for Health research program


Awarded by UK Medical Research Council


Awarded by US National Institutes of Health


Awarded by Medical Research Council


Awarded by National Institute for Health Research


Awarded by Chief Scientist Office


Funding Acknowledgements

We thank). Barrett and C. Wallace for the SNP selection. We thank the Wellcome Trust Sanger Institute Genotyping Facility, and, in particular, E. Gray, S. Bumpstead, D. Simpkin and H. Blackburn. Genotyping of the UK Rheumatoid Arthritis Genetics samples was supported by the Arthritis Research UK grant reference number 17552 and the Manchester Biomedical Research Centre. This work was made possible by funds from the Arthritis Foundation (S.R., principal investigator) and the US National Institutes Health (K08AR055688 to S.R. and 1R01AR062886-01 to P.I.W.d.B). P. Gilbert prepared the UK samples. Genotyping of the Swedish Umea samples was performed by the SNP&SEQ Technology Platform in Uppsala, which is supported by Uppsala University, Uppsala University Hospital, Science for Life Laboratory-Uppsala and the Swedish Research Council (contracts 80576801 and 70374401). This work was partially supported by the Redes Tematicas de Investigacion Cooperative en Salud (RETICS) Program, RD08/0075 (RIER), from the Instituto de Salud Carlos III, Spain. We acknowledge use of DNA from the UK Blood Services collection of Common Controls (UKBS-CC collection), which is funded by Wellcome Trust grant 076113/C/04/Z and by the US National Institutes for Health research program grant to the National Health Service Blood and Transplant (RP-PG-0310-1002). We acknowledge the use of DNA from the British 1958 Birth Cohort collection, which is funded by the UK Medical Research Council grant G0000934 and the Wellcome Trust grant 068545/Z/02. The North American Rheumatoid Arthritis Consortium and analysis of other US patient and control collections at the Feinstein Institute were supported by the US National Institutes of Health RO1-AR-4-4422, NO1-AR-2-2263; NO1-AR1-2256, RO1 AI068759 and RC2AR059092-01, with additional support from the Eileen Ludwig Greenland Center for Rheumatoid Arthritis and the family of Robert S. Boas. R.M.P. is supported by grants from the US National Institutes of Health (R01-AR057108, R01-AR056768, U01-GM092691 and R01-AR059648) and holds a Career Award for Medical Scientists from the Burroughs Wellcome Fund.