Journal article
Malaria, malnutrition, and birthweight: A meta-analysis using individual participant data
JE Cates, HW Unger, V Briand, N Fievet, I Valea, H Tinto, U D’Alessandro, SH Landis, S Adu-Afarwuah, KG Dewey, FO ter Kuile, M Desai, S Dellicour, P Ouma, J Gutman, M Oneko, L Slutsker, DJ Terlouw, S Kariuki, J Ayisi Show all
Plos Medicine | PUBLIC LIBRARY SCIENCE | Published : 2017
Abstract
Background: Four studies previously indicated that the effect of malaria infection during pregnancy on the risk of low birthweight (LBW; <2,500 g) may depend upon maternal nutritional status. We investigated this dependence further using a large, diverse study population. Methods and findings: We evaluated the interaction between maternal malaria infection and maternal anthropometric status on the risk of LBW using pooled data from 14,633 pregnancies from 13 studies (6 cohort studies and 7 randomized controlled trials) conducted in Africa and the Western Pacific from 1996–2015. Studies were identified by the Maternal Malaria and Malnutrition (M3) initiative using a convenience sampling appro..
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Grants
Awarded by National Institute of Child Health and Human Development
Funding Acknowledgements
[ "JC was funded by the National Institute of Allergy and Infectious Diseases at the National Institutes of Health (Pre-doctoral Training in Infectious Disease Epidemiology grant #5 T32 AI070114). The STOPPAM project, \"Strategies To Prevent Pregnancy-Associated Malaria,\" was by the European Union's Seventh Framework Programme (EU FP7); STOPPAM contract number: 200889. STOPPAM I (Benin) and STOPPAM II (Tanzania). The FSP/MISAME study (Burkina Faso) was funded by Nutrition Third World, The Belgium Ministry of Development, Flemish Interuniversity Council, and French Ministry of Development. The ECHO study (Democratic Republic of the Congo) was funded by the Department of Epidemiology, University of North Carolina Chapel Hill, UNC Gillings School of Global Public Health. The iLiNS-DYAD (Ghana) trial was funded by a grant to the University of California, Davis from the Bill & Melinda Gates Foundation. EMEP was partly supported by the Malaria in Pregnancy (MiP) Consortium, which is funded through a grant from the Bill & Melinda Gates Foundation to the Liverpool School of Tropical Medicine, UK and partly by the US Centers for Disease Control and Prevention (CDC), Division of Parasitic Diseases and Malaria through a cooperative agreement with Kenya Medical Research Institute (KEMRI), Center for Global Health Research (CGHR), Kisumu, Kenya. The IPTp-MON study (Kenya) was partly supported by the MiP Consortium, which is funded through a grant from the Bill & Melinda Gates Foundation to the Liverpool School of Tropical Medicine, UK and partly supported by the CDC. The ITN project (Kenya) was funded by the US Agency for International Development. The Special Health Support Fund from the Royal Netherlands Embassy (Nairobi, Kenya) provided additional support for the study of the impact of ITN in pregnancy. The Kisumu study (Kenya) was funded by US Agency for International Development (grants AOT0483-PH1-2171 and HRN-A-00-04- 00010-02) and the Netherlands Foundation for the Advancement of Tropical Research. The STOPMIP study (Kenya) was funded by the Malaria in Pregnancy (MiP) Consortium, which is funded through a grant from the Bill & Melinda Gates Foundation to the Liverpool School of Tropical Medicine, UK. The ISTp study (Malawi) was partly supported by the Malaria in Pregnancy (MiP) Consortium, which is funded through a grant from the Bill & Melinda Gates Foundation to the Liverpool School of Tropical Medicine, UK and partly funded by the European and Developing Countries Clinical Trials Partnership (EDCTP). The LAIS study was supported by grants from the Academy of Finland (grants 79787 and 207010), the Foundation for Pediatric Research in Finland, and the Medical Research Fund of Tampere University Hospital. Azithromycin and its placebo were provided free of charge by Pfizer Inc (New York, New York), which also provided funding for the polymerase chain reaction testing of the sexually transmitted infections. The IPTp study (Papua New Guinea [PNG]) was funded by the MiP Consortium, through a grant from the Bill & Melinda Gates Foundation (46099); the Pregvax Consortium, through a grant from the EU FP7- 2007-HEALTH (PREGVAX 201588) and the Spanish Government (EUROSALUD 2008 Programme); and Pfizer Inc., through an investigator-initiated research grant (WS394663). The Sek study (PNG) was supported by AusAID (grant to PNG Institute of Medical Research [IMR]), the National Health and Medical Research Council of Australia; Australian Research Council; Wellcome Trust; and Veterans Affairs Research Service.", "The Walter and Eliza Hall Institute is supported by the NHMRC Infrastructure for Research Institutes Support Scheme and Victorian State Government Operational Infrastructure Support. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript." ]