Journal article

Nomenclature and Serology of HLA Class I and Class II Alleles.

James McCluskey, Carmel Kanaan, Mary Diviney

Curr Protoc Immunol | Published : 2017

Abstract

This overview presents nomenclature and serology information on human leucocyte antigens, or HLA molecules, which are encoded by a cluster of genes linked on the short arm of chromosome 6. This region is known as the major histocompatibility complex and codes for class I and class II molecules, which are distinguished from each other based upon their structure, tissue distribution, and source of peptide antigen, as well as upon their interactions with T cell subsets. © 2017 by John Wiley & Sons, Inc.

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