Journal article

Application of the 2014 NICE cholesterol guidelines in the English population

Peter Ueda, Thomas Wai-Chun Lung, Philip Clarke, Goodarz Danaei

BRITISH JOURNAL OF GENERAL PRACTICE | ROYAL COLL GENERAL PRACTITIONERS | Published : 2017

Abstract

BACKGROUND: The 2014 guidelines on cardiovascular risk assessment and lipid modification from the National Institute for Health and Care Excellence (NICE) recommend statin therapy for adults with prevalent cardiovascular disease (CVD), and for adults with a 10-year CVD risk of ≥10%, estimated using the QRISK2 algorithm. AIM: To determine risk factor levels required to exceed the risk threshold for statin therapy, and to estimate the number of adults in England who would require statin therapy under the guidelines. DESIGN AND SETTING: Cross-sectional study using a sample representative of the English population aged 30-84 years. METHOD: To estimate 10-year CVD risk different combinations of r..

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Grants

Funding Acknowledgements

Peter Ueda was supported by the Swedish Society of Medicine and Galostiftelsen. Thomas Wai-Chun Lung received salary support as the HCF Research Foundation Postdoctoral Research Fellow. The Health Survey for England was funded by the Department of Health until 2004 and the Health and Social Care Information Centre from 2005. The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.