Journal article
An international comparison of retinopathy of prematurity grading performance within the Benefits of Oxygen Saturation Targeting II trials
BW Fleck, C Williams, E Juszczak, K Cocker, BJ Stenson, BA Darlow, S Dai, GA Gole, GE Quinn, DK Wallace, A Ells, S Carden, L Butler, D Clark, J Elder, C Wilson, S Biswas, A Shafiq, A King, P Brocklehurst Show all
Eye Basingstoke | NATURE PUBLISHING GROUP | Published : 2018
DOI: 10.1038/eye.2017.150
Abstract
PurposeTo investigate whether the observed international differences in retinopathy of prematurity (ROP) treatment rates within the Benefits of Oxygen Saturation Targeting (BOOST) II trials might have been caused by international variation in ROP disease grading.MethodsGroups of BOOST II trial ophthalmologists in UK, Australia, and New Zealand (ANZ), and an international reference group (INT) used a web based system to grade a selection of RetCam images of ROP acquired during the BOOST II UK trial. Rates of decisions to treat, plus disease grading, ROP stage grading, ROP zone grading, inter-observer variation within groups and intra-observer variation within groups were measured.ResultsForty..
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Awarded by Duke University
Funding Acknowledgements
The BOOST II trials were funded by the United Kingdom Medical Research Council, National Health and Medical Research Council of Australia, Health Research Council of New Zealand. The current study was funded by the Royal College of Surgeons Edinburgh, Royal Blind, and Edinburgh and Lothian Health Foundation.