Journal article

The global distribution of Crimean-Congo hemorrhagic fever

Jane P Messina, David M Pigott, Nick Golding, Kirsten A Duda, John S Brownstein, Daniel J Weiss, Harry Gibson, Timothy P Robinson, Marius Gilbert, GR William Wint, Patricia A Nuttall, Peter W Gething, Monica F Myers, Dylan B George, Simon I Hay

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | OXFORD UNIV PRESS | Published : 2015

Abstract

BACKGROUND: Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne infection caused by a virus (CCHFV) from the Bunyaviridae family. Domestic and wild vertebrates are asymptomatic reservoirs for the virus, putting animal handlers, slaughter-house workers and agricultural labourers at highest risk in endemic areas, with secondary transmission possible through contact with infected blood and other bodily fluids. Human infection is characterized by severe symptoms that often result in death. While it is known that CCHFV transmission is limited to Africa, Asia and Europe, definitive global extents and risk patterns within these limits have not been well described. METHODS: We used an exhaustive ..

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University of Melbourne Researchers

Grants

Awarded by Wellcome Trust


Awarded by Bill & Melinda Gates Foundation


Awarded by International Research Consortium on Dengue Risk Assessment Management and Surveillance (IDAMS)


Awarded by UK Medical Research Council (MRC)


Awarded by National Institutes of Health


Awarded by NATIONAL LIBRARY OF MEDICINE


Funding Acknowledgements

SIH is funded by a Senior Research Fellowship from the Wellcome Trust [#095066], which also supports AM and KAD, and a grant from the Bill & Melinda Gates Foundation [#OPP1093011]. JPM and SIH received funding from the International Research Consortium on Dengue Risk Assessment Management and Surveillance (IDAMS, [#21803], http://www.idams.eu). SIH would also like to acknowledge funding support from the RAPIDD program of the Science & Technology Directorate, Department of Homeland Security, and the Fogarty International Center, National Institutes of Health. PWG is a Career Development Fellow [#K00669X] jointly funded by the UK Medical Research Council (MRC) and the UK Department for International Development (DFID) under the MRC/DFID Concordat agreement and receives support from the Bill & Melinda Gates Foundation [#OPP1068048, #OPP1106023]. These grants also support DJW and HG. JSB is supported by a research grant from the National Library of Medicine, the National Institutes of Health [5R01LM010812-05]. DMP is funded by a Sir Richard Southwood Graduate Scholarship from the Department of Zoology at the University of Oxford. NG is funded by a grant from the Bill & Melinda Gates Foundation [#OPP1053338]. TPR is funded by the CGIAR Research Programmes on the Humidtropics, Climate Change, Agriculture and Food Security (CCAFS) and Agriculture for Nutrition and Health (A4NH).