Journal article

Predictors of cardiovascular events in patients with end-stage renal disease: an analysis from the Fosinopril in Dialysis study

Michele Kessler, Faiez Zannad, Philippe Lehert, Jean Pierre Gruenfeld, Christian Thuilliez, Alain Leizorovicz, Philippe Lechat

NEPHROLOGY DIALYSIS TRANSPLANTATION | OXFORD UNIV PRESS | Published : 2007

Abstract

BACKGROUND: Cardiovascular events (CVE) are a major cause of morbidity and mortality in end-stage renal disease (ESRD) patients. These patients are often excluded from CV clinical trials, and the prognostic factors associated with CVE in patients with ESRD have not been fully explored. A risk prediction model was created from the FOSIDIAL trial to identify factors predictive of CVE and to evaluate the relative strength of known predictors when considered together in a multivariate model. METHODS: FOSIDIAL was a prospective, randomized, double-blind study with 2-year follow-up and CVE adjudication. The study enrolled 397 patients with ESRD and left ventricular hypertrophy (LVH). CVE included ..

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