Journal article

Naftidrofuryl in intermittent claudication: a retrospective analysis.

P Lehert, S Comte, S Gamand, TM Brown

J Cardiovasc Pharmacol | Published : 1994


A retrospective analysis was performed on all five published clinical trials in which naftidrofuryl was given at a dosage of 600 mg daily. Two studies were undertaken in France, two in Germany, and one in Great Britain. Data for the analysis, which included the presence of risk factors, treadmill walking distances, and cardiovascular critical events that occurred during the course of the study, were generated from the patients' original study file. Included in the analysis were 888 patients, 447 receiving naftidrofuryl and 441 receiving placebo. Although there were significant differences between the studies with regard to certain variables, distribution was comparable between the treatment ..

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