Evaluation of a new assay for antibodies to LAV/HTLV III.
W Maskill, D Healey, A Wootten, C Silvester, S Johnson, C O'Dwyer, R Jacklin, R Pringle, I Gust, P Harden
Journal of Virological Methods | Published : 1986
The sensitivity, specificity and reproducibility of an enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to LAV/HTLV III produced by Genetic Systems was assessed with the identical panel of sera used in previous evaluations of anti-HTLV III ELISAs. The results from this study show that the Genetic Systems anti-LAV/HTLV III ELISA proved to be of equivalent sensitivity and to have higher specificity than assays currently used in Australia for screening purposes while maintaining high levels of intra- and inter-laboratory reproducibility.