Indirect immunofluorescence assay for the detection of hepatitis A virus-specific serum immunoglobulins.
DA Anderson, AG Coulepis, MP Chenoweth, ID Gust
Journal of Clinical Microbiology | Published : 1986
Hepatitis A virus-specific BSC-1 cells were used for the detection of serum immunoglobulins to hepatitis A virus by indirect immunofluorescence. Of 150 serum samples tested, specific immunoglobulin M was detected only in patients with serologically confirmed acute hepatitis A, while specific immunoglobulin G was detected in patients with acute or past clinical hepatitis A as well as many patients with no known history of hepatitis.