Patterns of migration indicate sexual transmission of HTLV‐I infection in non‐pregnant women in papua new guinea

Abstract

The prevalence of infection with human T‐cell leukaemia virus (HTLV‐I) was studied in Madang Province on the north coast of Papua New Guinea. Serum specimens collected from non‐pregnant women in 17 villages were tested for anti‐HTLV‐I by gelatin particle agglutination screening and confirmed by immunofluorescence and Western blotting. Overall, 13.9% of subjects were antibody‐positive, with the prevalence of antibodies varying from <10% to 30% in villages situated less than 10 km apart. Two groups of migrant women were identified, and in both a parity‐related increase in antibody prevalence which occurred only after marriage suggested that the predominant mode of transmission in migrant women..