Journal article
Visual Liver Score to Stratify Non-Alcoholic Steatohepatitis Risk and Determine Selective Intraoperative Liver Biopsy in Obesity
GJ Ooi, PR Burton, A Earnest, C Laurie, WW Kemp, PD Nottle, CA McLean, SK Roberts, WA Brown
Obesity Surgery | SPRINGER | Published : 2018
Abstract
Background: Non-alcoholic fatty liver disease (NAFLD) and its progressive form, non-alcoholic steatohepatitis (NASH), are endemic in obesity. We aimed to evaluate the diagnostic accuracy and reproducibility of a simple intraoperative visual liver score to stratify the risk of NASH and NAFLD in obesity and determine the need for liver biopsy. Methods: This is a prospective cohort study of obese adults undergoing bariatric surgery. The surgical team used a visual liver score to evaluate liver colour, size and surface. This was compared to histology from an intraoperative liver biopsy. Results: There were 152 participants, age 44.6 ± 12 years, BMI 45 ± 8.3 kg/m2. Prevalence of NAFLD was 70.4%, ..
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Funding Acknowledgements
GO, PB, CL and WB report being affiliated with the Centre for Obesity Research and Education. The centre has received funding for research purposes from Allergan and Apollo Endosurgery, the manufacturers of the LapBand (TM). The grant is not tied to any specific research project, and neither Allergan nor Apollo Endosurgery have control of the protocol, analysis and reporting of any studies. The centre also receives a grant from Applied Medical towards educational programs.GO reports scholarships from the National Health and Medical Research Council and the Royal Australasian College of Surgeons.