Molar Hypomineralisation: A Call to Arms for Enamel Researchers
Michael J Hubbard, Jonathan E Mangum, Vidal A Perez, Garry J Nervo, Roger K Hall
FRONTIERS IN PHYSIOLOGY | FRONTIERS MEDIA SA | Published : 2017
Developmental dental defects (DDDs, hereafter "D3s") hold significance for scientists and practitioners from both medicine and dentistry. Although, attention has classically dwelt on three other D3s (amelogenesis imperfecta, dental fluorosis, and enamel hypoplasia), dental interest has recently swung toward Molar Hypomineralisation (MH), a prevalent condition characterised by well-delineated ("demarcated") opacities in enamel. MH imposes a significant burden on global health and has potential to become medically preventable, being linked to infantile illness. Yet even in medico-dental research communities there is only narrow awareness of this childhood problem and its link to tooth decay, a..View full abstract
Support from the Melbourne Research Unit for Facial Disorders, Department of Pharmacology & Therapeutics (MH, JM, VP), Department of Paediatrics and Faculty of Medicine, Dentistry and Health Science (MH) at the University of Melbourne is gratefully acknowledged. JM holds a Peter Doherty early career fellowship from NHMRC Australia. VP additionally received PhD scholarship support in Melbourne from Becas Chile and the University of Talca where he now holds a faculty position.