Journal article

Atypical antipsychotics for disruptive behaviour disorders in children and youths (Review)

Jik H Loy, Sally N Merry, Sarah E Hetrick, Karolina Stasiak

COCHRANE DATABASE OF SYSTEMATIC REVIEWS | WILEY | Published : 2017

Abstract

BACKGROUND: This is an update of the original Cochrane Review, last published in 2012 (Loy 2012). Children and youths with disruptive behaviour disorders may present to health services, where they may be treated with atypical antipsychotics. There is increasing usage of atypical antipsychotics in the treatment of disruptive behaviour disorders. OBJECTIVES: To evaluate the effect and safety of atypical antipsychotics, compared to placebo, for treating disruptive behaviour disorders in children and youths. The aim was to evaluate each drug separately rather than the class effect, on the grounds that each atypical antipsychotic has different pharmacologic binding profile (Stahl 2013) and that t..

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