Journal article
De novo transcriptome assembly for the spiny mouse (Acomys cahirinus)
J Mamrot, R Legaie, SJ Ellery, T Wilson, T Seemann, DR Powell, DK Gardner, DW Walker, P Temple-Smith, AT Papenfuss, H Dickinson
Scientific Reports | NATURE PORTFOLIO | Published : 2017
Open access
Abstract
Spiny mice of the genus Acomys display several unique physiological traits, including menstruation and scar-free wound healing; characteristics that are exceedingly rare in mammals, and of considerable interest to the scientific community. These unique attributes, and the potential for spiny mice to accurately model human diseases, are driving increased use of this genus in biomedical research, however little genetic information is accessible for this species. This project aimed to generate a draft transcriptome for the Common spiny mouse (Acomys cahirinus). Illumina sequencing of RNA from 15 organ types (male and female) produced 451 million, 150 bp paired-end reads (92.4Gbp). An extensive ..
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Funding Acknowledgements
The authors would like to thank the following people for their contribution to the study: Daniel Cameron, Gerry Tonkin-Hill and all members of the Papenfuss lab; Steve Androulakis, and all members of the Monash Bioinformatics Platform; Vivien Vasic and members of the MHTP Medical Genomics Facility; and Walter and Eliza Hall Institute Department of Bioinformatics. This work was supported by the Victorian Government Operational Infrastructure Support Scheme and an Australian Research Council Discovery Grant to DWW and HD. JM is in receipt of a Faculty of Medicine, Nursing and Health Sciences Postgraduate Research Scholarship to undertake his PhD studies. HD is supported by a NHMRC Career Development Fellowship. DWW is supported by Cerebral Palsy Alliance.