PTPN2 regulates T cell lineage commitment and alpha beta versus gamma delta specification

Florian Wiede; Jarrod A Dudakov; Kun-Hui Lu; Garron T Dodd; Tariq Butt; Dale I Godfrey; Andreas Strasser; Richard L Boyd; Tony Tiganis

Journal article

PTPN2 regulates T cell lineage commitment and alpha beta versus gamma delta specification

Florian Wiede, Jarrod A Dudakov, Kun-Hui Lu, Garron T Dodd, Tariq Butt, Dale I Godfrey, Andreas Strasser, Richard L Boyd, Tony Tiganis

Journal of Experimental Medicine | ROCKEFELLER UNIV PRESS | Published : 2017

DOI: 10.1084/jem.20161903

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University of Melbourne Researchers

Dale Godfrey Author Microbiology and Immunology

Andreas Strasser Author Medical Biology (W.E.H.I.)

Tony Tiganis Author The Sir Peter MacCallum Department of Oncology

Garron Dodd Author Anatomy and Physiology

Related Projects (2)

RESEARCH FELLOWSHIP

Professor Godfrey is an immunologist with a long standing history as a pioneer in the study of a specialised type of white blood cell, known..

IMMUNE REGULATION EFFECTOR FUNCTION AND THERAPY

We seek to understand how white blood cells detect and destroy disease, and how molecules of the immune system punch holes in diseased cells..

Grants

Awarded by NHMRC of Australia

Awarded by Cancer Council Victoria

Awarded by NHMRC

Awarded by National Institutes of Health

Awarded by NATIONAL CANCER INSTITUTE

Funding Acknowledgements

This work was supported by the NHMRC of Australia (grant 1013667 to D.I. Godfrey, grant 1016701 to A. Strasser, and grant 1047055 to T. Tiganis) and the Cancer Council Victoria (grant 1106291 to A. Strasser and grant 1106477 to F. Wiede). D.I. Godfrey and A. Strasser are NHMRC Senior Principal Research Fellows (grants 1020770 and 1020363, respectively), and T. Tiganis is an NHMRC Principal Research Fellow (grant 1103037). J.A. Dudakov was supported by the National Institutes of Health (grant R00-CA176376), the Cuyamaca Foundation, the Bezos Family Foundation, and the Mechtild Harf Award from the Deutsche Knochenmarkspenderdatei Foundation for Giving Life.