Global, Regional, and National Burden of Rheumatic Heart Disease, 1990-2015
David A Watkins, Catherine O Johnson, Samantha M Colquhoun, Ganesan Karthikeyan, Andrea Beaton, Gene Bukhman, Mohammed H Forouzanfar, Christopher T Longenecker, Bongani M Mayosi, George A Mensah, Bruno R Nascimento, Antonio LP Ribeiro, Craig A Sable, Andrew C Steer, Mohsen Naghavi, Ali H Mokdad, Christopher JL Murray, Theo Vos, Jonathan R Carapetis, Gregory A Roth
NEW ENGLAND JOURNAL OF MEDICINE | MASSACHUSETTS MEDICAL SOC | Published : 2017
BACKGROUND: Rheumatic heart disease remains an important preventable cause of cardiovascular death and disability, particularly in low-income and middle-income countries. We estimated global, regional, and national trends in the prevalence of and mortality due to rheumatic heart disease as part of the 2015 Global Burden of Disease study. METHODS: We systematically reviewed data on fatal and nonfatal rheumatic heart disease for the period from 1990 through 2015. Two Global Burden of Disease analytic tools, the Cause of Death Ensemble model and DisMod-MR 2.1, were used to produce estimates of mortality and prevalence, including estimates of uncertainty. RESULTS: We estimated that there were 31..View full abstract
Supported by a grant from the Bill and Melinda Gates Foundation and by the Medtronic Foundation (to Dr. Watkins).