Regional left ventricular function does not predict survival in ischaemic cardiomyopathy after cardiac surgery
David L Prior, Susanna R Stevens, Thomas A Holly, Michal Krejca, Alexandros Paraforos, Gerald M Pohost, Krysti Byrd, Tomasz Kukulski, Robert H Jones, Patrice Desvigne-Nickens, Padmini Varadarajan, Aman Amanullah, Grace Lin, Hussein R Al-Khalidi, Gabriel Aldea, Carlo Santambrogio, Andrzej Bochenek, Daniel S Berman
HEART | BMJ PUBLISHING GROUP | Published : 2017
OBJECTIVES: To define the prognostic contribution of global and regional left ventricular (LV) function measurements in patients with ischaemic cardiomyopathy randomised to coronary artery bypass graft surgery (CABG) with (n=501) or without (n=499) surgical ventricular reconstruction (SVR). METHODS: Novel multivariable methods to analyse global and regional LV systolic function were used to better formulate prediction models for long-term mortality following CABG with or without SVR in the entire cohort of 1000 randomised SVR hypothesis patients. Key clinical variables were included in the analysis. Regional function was classified according to the discreteness of anteroapical hypokinesia an..View full abstract
Awarded by National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
Awarded by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
This work was supported by Grants U01-HL69015, U01-HL69013 and R01-HL105853 from the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.