Sequential changes in the metabolic response to orthotopic liver transplantation during the first year after surgery.
LD Plank, DJ Metzger, JL McCall, KL Barclay, EJ Gane, SJ Streat, SR Munn, GL Hill
Ann Surg | Published : 2001
OBJECTIVE: To quantify the sequential changes in the metabolic response occurring in patients with end-stage liver disease after orthotopic liver transplantation (OLT). SUMMARY BACKGROUND DATA: Detailed quantification of the changes in energy expenditure, body composition, and physiologic function that occur in patients after OLT has not been performed. Understanding these changes is essential for the optimal management of these patients. METHODS: Fourteen patients who underwent OLT for end-stage liver disease had measurements of resting energy expenditure, body composition, and physiologic function immediately before surgery and 5, 10, 15, 30, 90, 180, and 360 days later. RESULTS: Resting e..View full abstract