Journal article

Corticosteroids in the management of bowel obstruction on a gynecological oncology unit

J Philip, N Lickiss, PT Grant, NF Hacker

GYNECOLOGIC ONCOLOGY | ACADEMIC PRESS INC | Published : 1999

Abstract

The development of gastrointestinal obstruction commonly occurs as a complication of advanced gynecological cancer. While surgery remains the mainstay of treatment for these patients, it is not always feasible, and when it is performed, it does not always resolve the obstruction. In this prospective study of patients presenting to a gynecologic oncology unit, 13 patients were administered 8 mg of dexamethasone subcutaneously or intravenously for a minimum of 3 days to manage the symptoms of bowel obstruction. Nine patients (69%) had a response to this therapy with decreased pain, nausea, and vomiting and improved oral intake. This response was maintained for a median of 31 days, with 7 of th..

View full abstract