Journal article

The Characterisation of Pluripotent and Multipotent Stem Cells Using Fourier Transform Infrared Microspectroscopy

Julie Cao, Elizabeth S Ng, Donald McNaughton, Edouard G Stanley, Andrew G Elefanty, Mark J Tobin, Philip Heraud

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | MDPI | Published : 2013

Abstract

Fourier transform infrared (FTIR) microspectroscopy shows potential as a benign, objective and rapid tool to screen pluripotent and multipotent stem cells for clinical use. It offers a new experimental approach that provides a holistic measurement of macromolecular composition such that a signature representing the internal cellular phenotype is obtained. The use of this technique therefore contributes information that is complementary to that acquired by conventional genetic and immunohistochemical methods.