Single-step nonlinear diffusion tensor estimation in the presence of microscopic and macroscopic motion.
Murat Aksoy, Chunlei Liu, Michael E Moseley, Roland Bammer
Magn Reson Med | Published : 2008
Patient motion can cause serious artifacts in diffusion tensor imaging (DTI), diminishing the reliability of the estimated diffusion tensor information. Studies in this field have so far been limited mainly to the correction of miniscule physiological motion. In order to correct for gross patient motion it is not sufficient to correct for misregistration between successive shots; the change in the diffusion-encoding direction must also be accounted for. This becomes particularly important for multishot sequences, whereby-in the presence of motion-each shot is encoded with a different diffusion weighting. In this study a general mathematical framework to correct for gross patient motion prese..View full abstract