Journal article

Vertebral metastases: assessment with apparent diffusion coefficient.

Andreas M Herneth, Marcel O Philipp, Jonathan Naude, Martin Funovics, Reinhard R Beichel, Roland Bammer, Herwig Imhof

Radiology | Published : 2002


The authors evaluated the apparent diffusion coefficient (ADC) in the assessment of vertebral metastases and acute vertebral compression fractures in 22 patients with known or suspected vertebral metastases. On the basis of significantly (P <.03) different ADCs, vertebral metastases (0.69 x 10(-3) mm2/sec) and pathologic compression fractures (0.65 x 10(-3) mm2/sec) can be safely distinguished from vertebral bodies (1.66 x 10(-3) mm2/sec) and benign compression fractures (1.62 x 10(-3) mm2/sec). Thus, the use of ADCs may increase the specificity of magnetic resonance imaging in these patients.

University of Melbourne Researchers