Journal article

Temporal and spatial profile of brain diffusion-weighted MRI after cardiac arrest.

Michael Mlynash, Dennis M Campbell, Emily M Leproust, Nancy J Fischbein, Roland Bammer, Irina Eyngorn, Amie W Hsia, Michael Moseley, Christine AC Wijman

Stroke | Published : 2010


BACKGROUND AND PURPOSE: Diffusion-weighted magnetic resonance imaging of the brain is a promising technique to help predict functional outcome in comatose survivors of cardiac arrest. We aimed to evaluate prospectively the temporal-spatial profile of brain apparent diffusion coefficient changes in comatose survivors during the first 8 days after cardiac arrest. METHODS: Apparent diffusion coefficient values were measured by 2 independent and blinded investigators in predefined brain regions in 18 good- and 15 poor-outcome patients with 38 brain magnetic resonance imaging scans and were compared with those of 14 normal controls. The same brain regions were also assessed qualitatively by 2 oth..

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University of Melbourne Researchers