Improvements in parallel imaging accelerated functional MRI using multiecho echo-planar imaging.
Heiko Schmiedeskamp, Rexford D Newbould, Laura J Pisani, Stefan Skare, Gary H Glover, Klaas P Pruessmann, Roland Bammer
Magn Reson Med | Published : 2010
Multiecho echo-planar imaging (EPI) was implemented for blood-oxygenation-level-dependent functional MRI at 1.5 T and compared to single-echo EPI with and without parallel imaging acceleration. A time-normalized breath-hold task using a block design functional MRI protocol was carried out in combination with up to four echo trains per excitation and parallel imaging acceleration factors R = 1-3. Experiments were conducted in five human subjects, each scanned in three sessions. Across all reduction factors, both signal-to-fluctuation-noise ratio and the total number of activated voxels were significantly lower using a single-echo EPI pulse sequence compared with the multiecho approach. Signal..View full abstract