Smoking cessation in pregnancy and the risk of child behavioural problems: a longitudinal prospective cohort study
Monique Robinson, Neil J McLean, Wendy H Oddy, Eugen Mattes, Max Bulsara, Jianghong Li, Stephen R Zubrick, Fiona J Stanley, John P Newnham
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH | B M J PUBLISHING GROUP | Published : 2010
BACKGROUND: The aim of this study was to examine the influence of smoking in pregnancy on child and adolescent behavioural development, in comparison with mothers who ceased smoking in the first 18 weeks of pregnancy and with those who never smoked, in a large prospective pregnancy cohort. METHODS: The Western Australian Pregnancy Cohort (Raine) Study provided comprehensive data from 2900 pregnancies. Smoking was assessed at 18 weeks gestation, and children were followed up at ages 1, 2, 3, 5, 8, 10 and 14 years. The Child Behaviour Checklist (CBCL) was used to measure problem child behaviour with continuous z-scores and clinical cut points at ages 2, 5, 8, 10 and 14 years. Potential confoun..View full abstract
The Western Australian Pregnancy Cohort (Raine) Study is funded by the Raine Medical Research Foundation at The University of Western Australia, the National Health and Medical Research Council of Australia (NHMRC), the Telstra Foundation, the Western Australian Health Promotion Foundation, and the Australian Rotary Health Research Fund. We would also like to acknowledge the Telethon Institute for Child Health Research and the NHMRC Program Grant which supported the 14-year follow-up (Stanley et al ID 003209).