Journal article

Atopy, eczema and breast milk fatty acids in a high-risk cohort of children followed from birth to 5 yr

WH Oddy, S Pal, MMH Kusel, D Vine, NH de Klerk, P Hartmann, PG Holt, PD Sly, PR Burton, FJ Stanley, LI Landau

PEDIATRIC ALLERGY AND IMMUNOLOGY | WILEY | Published : 2006

Abstract

BACKGROUND: The incidence of atopic diseases such as eczema is increasing in westernized societies. The suggestion that there is a "protective" association between the unique fatty acid composition of breast milk, particularly the omega-3 (n-3) and omega-6 (n-6) essential polyunsaturated fatty acid content, and the development of atopic disease in children was investigated in a cohort study of 263 infants born into families with a history of allergy (one or both parents had asthma, hayfever, eczema). The objectives of this study were to determine the lipid profile [specifically in relation to long-chain polyunsaturated fatty acid (LC-PUFA) composition] in maternal breast milk samples collect..

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