Accuracy of second trimester prediction of preterm preeclampsia by three different screening algorithms

Abstract

Aim: To compare the performance of three different screening methods (National Institute for Health and Clinical Excellence (NICE) guidelines, American College of Obstetricians and Gynecologists (ACOG) recommendations and Fetal Medicine Foundation (FMF) algorithm) for second trimester prediction of preeclampsia. Methods: This was a prospective non-intervention study in singleton pregnancies, including women attending for second trimester morphologic ultrasound at 19–22 weeks. Maternal characteristics, medical history, mean arterial pressure and mean uterine artery Doppler pulsatility index were recorded and used for risk assessment. Outcomes measured were preeclampsia with delivery before 34..