Journal article

High-dose compared with low-dose oxytocin for induction of labour of nulliparous women at term

Natasha Prichard, Anthea Lindquist, Richard Hiscock, Sophie Ruff, Stephen Tong, Fiona C Brownfoot

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | TAYLOR & FRANCIS LTD | Published : 2019

Abstract

BACKGROUND: The optimal oxytocin infusion regimen to induce labour with the lowest caesarean section rate, instrumental delivery rate and length of active labour is unclear. We compared the effect of a low-dose to high-dose oxytocin regimen to induce labour. MATERIALS AND METHODS: We conducted a retrospective study of nulliparous women induced at term in a single tertiary centre from 2009 to 2015. The oxytocin induction protocol changed from a high to low-dose regimen in November 2012, affording us the opportunity to compare outcomes 3 years prior to, and following the change in protocol. Main outcome measures were caesarean section rate, instrumental delivery rate and length of active labou..

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Grants

Awarded by National Health and Medical Research Council of Australia


Funding Acknowledgements

F. B. was supported by an Australian Postgraduate Award, an AVANT scholarship, an Arthur Wilson Memorial Scholarship and by the Medical Research Foundation for Women and Babies. S. T. was supported by the National Health and Medical Research Council of Australia (# 1050765). N. P. was supported by an AVANT scholarship. The funders had no role in study design, data collection, analysis, decision to publish or preparation of the manuscript.