Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia

M Waibel; SJ Vervoort; IY Kong; S Heinzel; KM Ramsbottom; BP Martin; ED Hawkins; RW Johnstone

Journal article

Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia

M Waibel, SJ Vervoort, IY Kong, S Heinzel, KM Ramsbottom, BP Martin, ED Hawkins, RW Johnstone

Leukemia | NATURE PUBLISHING GROUP | Published : 2018

DOI: 10.1038/leu.2017.282

University of Melbourne Researchers

DR Stephanus Vervoort Author

DR Susanne Heinzel Author

A/Prof Edwin Hawkins Author

Prof Ricky Johnstone Author

Grants

Funding Acknowledgements

The work was funded by the Australian National Health and Medical Research Council. MW was supported by a fellowship from the Deutsche Forschungsgemeinschaft and funding from the NHMRC. SJV was funded by a Rubicon fellowship from the Netherlands Organization for Scientific Research. EDH was supported by a fellowship from the National Health and Medical Research Council of Australia. RWJ was supported by a National Health and Medical Research Council (NHMRC) Senior Principal Research Fellowship, project and program grants from the NHMRC, the Cancer Council Victoria and the Victorian Cancer Agency. EDH would like to thank Sarah Russell for mentorship through the project.